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Symptoms of a Manic Phase |
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Increased physical and mental activity
Heightened mood
Excessive irritability
Decreased need for sleep
Grandiose delusions
Racing speech
Impulsiveness
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Causes

Genes may increase the chances of developing bipolar. As with many mental illnesses, genes determine how vulnerable someone might be to a condition. But environmental factors such as stress are often the triggers that are linked to its development. But these triggers do not seem to set off the development of bipolar episodes or disorder in everyone with genes for this condition. Scientists are trying to find out why.
Bipolar episodes can be triggered by:
- Substance use
Cocaine, steroids, amphetamines, hallucinogens.
- Medications
Isoniazid, steroids, disulfiram, amphetamines, cimetidine, levodopa, methylphenidate, opioids.
- Nerve conditions
Multiple sclerosis, serious head injury, CNS tumors, epilepsy, Huntington's chorea, post stroke, migraines, Wilson's disease, lupus.
- Metabolic conditions
Thyroid disorders, postoperative states, adrenal disorders, vitamin B12 deficiency, electrolyte abnormalities.
- Infections
AIDS, dementia, neurosyphilis, influenza.
More on Bipolar Disorder Bipolar By-Product: Substance Abuse
In the Encyclopedia: Antipsychotic drugs Antipsychotic drugs, atypical Tardive dyskinesia
This article was reviewed and updated June 2007.
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